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Language and Motor f MRI Activation in Polymicrogyric Cortex
Author(s) -
Araujo David,
De Araujo Draulio B.,
PontesNeto Octavio M.,
EscorsiRosset Sara,
Simao Gustavo N.,
WichertAna Lauro,
Velasco Tonicarlo R.,
Sakamoto Americo C.,
Leite Joao P.,
Santos Antonio C.
Publication year - 2006
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/j.1528-1167.2006.00473.x
Subject(s) - polymicrogyria , motor cortex , cortex (anatomy) , epilepsy , neuroscience , epilepsy surgery , supplementary motor area , psychology , medicine , functional magnetic resonance imaging , stimulation
Summary: Purpose: To analyze the patterns of brain activation in polymicrogyric cortex in epilepsy patients by blood oxygenation level–dependent (BOLD) functional MRI ( f MRI), during language and motor activation tasks. Methods: Five patients with extratemporal epilepsy associated with polymicrogyria were scanned in a 1.5‐T Siemens scanner with BOLD f MRI sequences, by following language and motor paradigms. Functional images were processed by using Brain Voyager software. Results: Activation of polymicrogyric cortex in the brain area that corresponds to the motor strip was present in all patients. Language studies revealed activation of polymicrogyric cortex over Broca's area in three cases. Conclusions: Functionality was shown in polymicrogyric areas. Therefore if surgical resection is indicated, a careful functional planning is necessary because of functionality of the polymicrogyric cortex.