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Hyponatremia Associated with Repeated Use of Levetiracetam
Author(s) -
Nasrallah Khalil,
Silver Brian
Publication year - 2005
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/j.1528-1167.2005.64004.x
Subject(s) - levetiracetam , hyponatremia , somnolence , medicine , antidiuretic , anticonvulsant , anesthesia , syndrome of inappropriate antidiuretic hormone secretion , toxicity , pediatrics , epilepsy , adverse effect , hormone , psychiatry
Summary: Levetiracetam (LEV) is increasingly used as adjunctive anticonvulsant therapy because of apparent low toxicity. Somnolence, asthenia, headache, dizziness, and nervousness are the most frequently reported side effects (1). We describe a patient, predisposed to the development of the syndrome of inappropriate antidiuretic hormone secretion (SIADH), in whom hyponatremia developed after two challenges of LEV.