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Late Seizure Recurrence after Multiple Subpial Transections
Author(s) -
Orbach Darren,
Romanelli Pantaleo,
Devinsky Orrin,
Doyle Werner
Publication year - 2001
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/j.1528-1167.2001.45300.x
Subject(s) - epilepsy surgery , refractory (planetary science) , epilepsy , medicine , surgery , anesthesia , central nervous system disease , psychiatry , physics , astrobiology
Summary: We studied long‐term outcome (range, 28–89 months; mean, 56 months) after multiple subpial transections (MSTs) for medically refractory epilepsy. Forty‐three (79.6%) of 54 patients had a consistent significant reduction in seizure frequency, and 27 (50%) of the 54 were either entirely seizure free or virtually so. However, 10 (18.6%) patients sustained an increase in seizure frequency several years after surgery, after showing initial postoperative improvement. This suggests that late seizure recurrence is a more important problem in cases in which MST has been performed than for pure resections.