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Benign Focal Epilepsies of Childhood: Genetically Determined Pathophysiology—Epilepsy That Comes and Goes
Author(s) -
Prince David A.
Publication year - 2000
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/j.1528-1157.2000.tb00310.x
Subject(s) - epilepsy , pathophysiology , neuroscience , childhood absence epilepsy , psychology , medicine , pathology
Developmental processes; the types of neuron expressing particular gene products; the sites of these receptors/channels, transporters, etc., on neurons and in circuits; and compensatory processes such as activation of other genes, sprouting, pruning, and receptor plasticity will determine the nature of the epileptic phenotype induced by a particular genetic alteration, and the ultimate functional outcome.