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Electrical Stimulation of the Contralateral Mesial Temporal Structure Induces an Ipsilateral Seizure Pattern in Mesial Temporal Lobe Epilepsy
Author(s) -
Inoue Yushi,
Mihara Tadahiro,
Tottori Takayasu,
Seino Masakazu
Publication year - 1999
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/j.1528-1157.1999.tb02046.x
Subject(s) - temporal lobe , stimulation , epilepsy , mesial temporal lobe epilepsy , psychology , electroencephalography , neuroscience , lobe , medicine , anatomy
Summary:Purpose: We examined the mode of seizure development induced by electrical stimulation in patients with mesial temporal lobe epilepsy. Methods: Of 25 patients undergoing intracranial EEG evaluation and electrical stimulation ipsilateral to the presumed site of habitual seizure origin, 17 patients had additional stimulation studies on the contralateral temporal lobe. Results: Fourteen of the 25 patients had seizures induced with ipsilateral stimulation, and two of the 17 patients had seizures with contralateral stimulation. Seizures induced by ipsilateral stimulation started in the ipsilateral temporal lobe, whereas those induced by contralateral stimulation originated from the ipsilateral temporal lobe structure and were identical to the habitual seizures. Conclusions: Electrical stimulation of the temporal lobe structure opposite the site of habitual seizure origin is said to induce a seizure rarely. However, according to our preliminary results, if contralateral stimulation elicits a habitual seizure in the ipsilateral temporal lobe, it might be considered additional confirmatory evidence of seizure lateralization.