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The Challenges of Epilepsy in Children
Author(s) -
Dulac Olivier,
Bulteau Christine,
Pedersen Søren,
Uldall Peter
Publication year - 1997
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/j.1528-1157.1997.tb04525.x
Subject(s) - epilepsy , cognition , epilepsy syndromes , medicine , electroencephalography , clinical trial , antiepileptic drug , incidence (geometry) , pediatrics , psychology , psychiatry , intensive care medicine , physics , optics
Summary: Among the most distinct and challenging characteristics of childhood epilepsy are the high incidence, the risk of cognitive function deterioration, the age relationship of various types of epilepsy, and the existence of particular clinical and EEG patterns that characterize epilepsy syndromes. With regard to antiepileptic drug (AED) treatment, one must take into account age‐dependent pharmacokinetics, response to treatment according to the type of epilepsy, and ethical constraints in the development of controlled trials that often prevent the early introduction of new AEDs to the pediatric market.