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Wavelength Specificity of Photoparoxysmal Responses in Idiopathic Generalized Epilepsy
Author(s) -
Takahashi Yukitoshi,
Fujiwara Tateki,
Yagi Kazuichi,
Seino Masakazu
Publication year - 1995
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/j.1528-1157.1995.tb00466.x
Subject(s) - flashing , wavelength , epilepsy , medicine , ophthalmology , optics , chemistry , physics , psychiatry
Summary: Using optic filters, we analyzed the wavelength specificity of photoparoxysmal responses (PPR) in photosensitive patients with idiopathic generalized epilepsy (ICE). We specified the wavelength spectrum ∼700 nm (660–720 nm) as the only visible spectrum essential for eliciting PPR in some normal trichromat IGE patients and showed that any flashing lights containing this essential wavelength spectrum could elicit PPR independent of the number of stimulated cones. Absorption of the wavelength spectrum ‐700 nm by optic filters eliminated PPR in normal trichromat ICE patients. In an IGE patient with deuteranomaly, intermittent flashing lights containing a part of the wavelength spectrum from 580 to 700 nm elicited PPR. These data suggest a new interpretation of wavelength specificity of PPR: Flashing lights containing the wavelength spectrum that does not produce antagonistic cone interactions at the level of retinal ganglion cells can elicit PPR in some photosensitive ICE patients.