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Major Patterns of Human Inheritance: Relevance to the Epilepsies
Author(s) -
Bird Thomas D.
Publication year - 1994
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/j.1528-1157.1994.tb05924.x
Subject(s) - mendelian inheritance , anticipation (artificial intelligence) , biology , inheritance (genetic algorithm) , non mendelian inheritance , imprinting (psychology) , genomic imprinting , genetics , multifactorial inheritance , human genetics , relevance (law) , evolutionary biology , gene , single nucleotide polymorphism , computer science , mitochondrial dna , dna methylation , gene expression , artificial intelligence , genotype , law , political science
Summary: An understanding of the basic principles of human inheritance patterns is necessary to appreciate the variety and complexity of genetic influences in the epilepsies. The various modes of human inheritance include single gene (mendelian), chromosomal, mitochondrial, and multifactorial/polygenic. Recent insights regarding imprinting, anticipation, and uniparental disomy have been made and have an impact on our understanding of human genetics. All of these phenomena are likely to be of importance in the epilepsies and form the basis for a more detailed analysis of the relevant molecular biology.