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Global Aphasia with Seizure Onset in the Dominant Basal Temporal Region
Author(s) -
AbouKhalil Bassel,
Welch Larry,
Blumenkopf Bennett,
Newman Karen,
Whetsell William O.
Publication year - 1994
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/j.1528-1157.1994.tb02558.x
Subject(s) - ictal , epilepsy , aphasia , psychology , semiology , neuroscience , electroencephalography , ictal interictal spect analysis by spm , audiology , basal (medicine) , medicine , insulin
Summary: A 33‐year‐old right‐handed woman had intractable simple and complex partial seizures (SPS, CPS) that began with global aphasia. EEG closed‐circuit TV (EEG‐CCTV) monitoring with sphenoidal electrodes showed left inferomesial temporal ictal onset of CPS. Subdural electrodes were implanted over the left frontotemporal convexity, sub temporally and subfrontally. Stimulation of the basotemporal cortex produced global aphasia. A posterolaterotemporal language area was also identified. Spontaneous SPS had focal onset in the basal temporal language area (BTLA). Ictal discharges did not involve the posterotemporal region. This case shows that aphasic speech arrest at seizure onset may be due to seizure discharge in the basotemporal region and that the BTLA is clinically relevant in seizure semiology.