Premium
Acute Cholangitis Induced by Carbamazepine
Author(s) -
Spina I.,
Secchi P.,
Grampa G.,
Uccellini D.,
Porazzi D.
Publication year - 1994
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/j.1528-1157.1994.tb02550.x
Subject(s) - carbamazepine , cholestasis , adverse effect , gastroenterology , medicine , hepatic function , anticonvulsant , epilepsy , anesthesia , psychiatry
Summary: We report a case of a patient with fever and intrahepatic cholestasis induced by carbamazepine (CBZ). This adverse reaction has been described in only a single case. We observed complete resolution of the hepatic damage once the agent was discontinued. CBZ rechallenge was followed by recurrence of all symptoms and abnormalities. Hepatic function improved again when CBZ was discontinued.