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Submandibular Salivary Gland Hypertrophy Induced by Phenytoin
Author(s) -
Brandenburg A. H.,
Smits M. G.,
Voorbrood B. S.,
Hemmes A. M.,
Ros J. J. W.
Publication year - 1993
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/j.1528-1157.1993.tb02388.x
Subject(s) - phenytoin , muscle hypertrophy , submandibular gland , salivary gland , discontinuation , medicine , endocrinology , salivary gland diseases , epilepsy , psychiatry
Summary: A 16‐year‐old boy with epilepsy developed hypertrophy of the submandibular salivary glands, with high phenytoin (PHT) serum levels. The submandibular salivary glands became normal in 12 days after discontinuation of PHT. Other causes of salivary gland hypertrophy were excluded and we suggest that the hypertrophy was due to PHT.