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Temporal Lobe Epilepsy in Early Childhood
Author(s) -
Wyllie Elaine,
Chee Michael,
Granstrom MarjaLiisa,
DelGiudice Ennio,
Estes Melinda,
Comair Youssef,
Pizzi Margaret,
Kotagal Prakash,
Bourgeois Blaise,
Lüders Hans
Publication year - 1993
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/j.1528-1157.1993.tb02103.x
Subject(s) - epilepsy , temporal lobe , neuroscience , medicine , psychology , clinical neurology , audiology
Summary: To explore the electroclinical features of temporal lobe epilepsy (TLE) in early childhood, we studied results of video‐EEG and other tests of 14 children aged 16 months to 12 years selected by seizure‐free outcome after temporal lobectomy. Four children had mesiotemporal sclerosis, 1 had cortical dysplasia, and 9 had low‐grade temporal neoplasms. The children had complex partial seizures (CPS) with symptomatology similar to that of adults with TLE, including decreased responsiveness and automatisms. Automatisms tended to be simpler in the younger children, typically limited to lip smacking and fumbling hand gestures. Scalp/sphenoidal EEC showed anterior/inferior temporal interictal sharp waves and unilateral temporal seizure onset in the 4 children with mesiotemporal sclerosis and in the child with cortical dysplasia, but EEG findings in 9 children with low‐grade temporal tumors were complex, including multifo‐cal interictal sharp waves or poorly localized or falsely lateralized EEG seizure onset. In children without tumors, video‐EEG was critical to localization of the epi‐leptogenic zone for resection, but in patients with tumors video‐EEG was less localizing and its main value was to confirm that the reported behaviors were epileptic seizures with semiology typical of temporal lobe onset.