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Progressive Unilateral Encephalopathy of Childhood (Rasmussen's Syndrome): A Reappraisal
Author(s) -
Vining Eileen P. G.,
Freeman John M.,
Brandt Jason,
Carson Benjamin S.,
Uematsu Sumio
Publication year - 1993
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/j.1528-1157.1993.tb00441.x
Subject(s) - hemispherectomy , etiology , encephalopathy , pediatrics , psychology , west syndrome , medicine , epilepsy , developmental psychology , neuroscience , psychiatry
Summary: Twelve children with Rasmussen's encephalitis underwent hemispherectomy and have been followed for an average of 9.15 years. Our decision‐making process leads to early, rather than late operation. Because hemiplegia is inevitable with or without operation, earlier operation may allow such children to resume a more normal life. We postulate that earlier operation may prevent some of the intellectual decline that accompanies the continued seizures and their treatment. In view of the variable pathologic findings and lack of evidence of a viral etiology, we suggest either use of the term “progressive unilateral encephalopathy of childhood” or “Rasmussen's syndrome” in recognition of its heritage.