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Seizures in a Fetal Lamb After Cocaine Exposure: A Case Report
Author(s) -
Peters Aemil J. M.,
Abrams Robert M.,
Burchfield David J.,
Gilmore Robin L.
Publication year - 1992
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/j.1528-1157.1992.tb01750.x
Subject(s) - medicine , fetus , epilepsy , cocaine use , psychology , pregnancy , psychiatry , genetics , biology
Summary: We report the chance observation of two generalized seizures in a fetal lamb that received cocaine. Cocaine was infused intravenously into a 138‐day‐old fetus while electrocortical (ECoG), electroocular (EOG), and neck electromyographic (EMG) activity were recorded. Fetal rapid eye movement (REM) and nonrapid eye movement (NREM) sleep were disrupted during the cocaine exposure and returned to a normal pattern after infusions were stopped. Seventy‐two hours later, however, we recorded generalized seizures with ECoG spike and spike wave activity.