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EEG and Seizures in Children with Hemolytic–Uremic Syndrome
Author(s) -
Dhuna A.,
PascualLeone A.,
Talwar D.,
Torres F.
Publication year - 1992
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/j.1528-1157.1992.tb01696.x
Subject(s) - prodrome , electroencephalography , epilepsy , pediatrics , psychology , lateralization of brain function , complex partial seizures , medicine , audiology , anesthesia , temporal lobe , psychosis , neuroscience , psychiatry
Summary: The EEG results of 11 children, ages 1–15 years, who presented with hemolytic‐uremic syndrome complicated by seizures 3–10 days after the prodrome were studied. In four children who experienced generalized tonic‐clonic seizures, the EEGs demonstrated diffuse delta slowing with no focality. All recovered without neurological deficits or a residual seizure disorder. Of seven children who experienced partial seizures, six had structural lesions on cranial computed tomography and residual focal neurological deficits with epilepsy. The EEGs in two patients revealed focal spikes and slowing consistent with the lateralization of the partial seizures, in four it was characterized by atypical “burst suppression,” and in one showed epochs of high‐amplitude delta slowing alternating with generalized suppression. Although episodic and generalized burst suppression is usually regarded as a grave prognostic indicator, all four subjects recovered.