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Simultaneous Quantitative Determination of Anti‐Epileptic Drugs, Including Carbamazepine, in Body Fluids
Author(s) -
MEIJER J. W. A.
Publication year - 1971
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/j.1528-1157.1971.tb04382.x
Subject(s) - carbamazepine , chromatography , drug , epilepsy , anticonvulsant , chemistry , medicine , pharmacology , psychiatry
SUMMARY A gas chromatographic procedure is described for routine measurement of anti‐epileptic drugs, including carbamazepine, in body fluids of patients treated with a number of these drugs simultaneously. Problems involved in the selection of the gas chromatographic conditions, internal standards and the elimination of interfering substances are described.