Open AccessTolperisone: A Typical Representative of a Class of Centrally Acting Muscle Relaxants with Less Sedative Side Effects
Author(s) -
Quasthoff Stefan,
Möckel Claudia,
Zieglgänsberger Walter,
Schreibmayer Wolfgang
Publication year - 2008
Publication title -
cns neuroscience and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.403
H-Index - 69
eISSN - 1755-5949
pISSN - 1755-5930
DOI - 10.1111/j.1527-3458.2008.00044.x
Subject(s) - sedative , medicine , pharmacodynamics , pharmacology , muscle relaxant , pharmacokinetics , anesthesia
Tolperisone, a piperidine derivative, is assigned to the group of centrally acting muscle relaxants and has been in clinical use now for decades. The review summarizes the known pharmacokinetics, pharmacodynamics, toxicology and side effects in humans and the clinical use of tolperisone. A future perspective for further exploration of this drug is given.