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Ten Years of Rizatriptan: From Development to Clinical Science and Future Directions
Author(s) -
Hargreaves Richard J.,
Lines Chris R.,
Rapoport Alan M.,
Ho Tony W.,
Sheftell Fred D.
Publication year - 2009
Publication title -
headache: the journal of head and face pain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.14
H-Index - 119
eISSN - 1526-4610
pISSN - 0017-8748
DOI - 10.1111/j.1526-4610.2008.01335.x
Subject(s) - rizatriptan , medicine , migraine , field (mathematics) , medical physics , intensive care medicine , sumatriptan , mathematics , receptor , agonist , pure mathematics
The year 2008 marked the 10th anniversary since rizatriptan was first launched for the acute treatment of migraine. In this article we discuss the concepts that motivated the preclinical and clinical development of rizatriptan, the clinical evidence that has driven its use over the past decade, rizatriptan's overall contribution to the field, and future directions for research.