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Expert Opinion: Beta‐Blockers for Migraine
Author(s) -
Evans Randolph W.,
Rizzoli Paul,
Loder Elizabeth,
Bana Dhirendra
Publication year - 2008
Publication title -
headache: the journal of head and face pain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.14
H-Index - 119
eISSN - 1526-4610
pISSN - 0017-8748
DOI - 10.1111/j.1526-4610.2007.01046.x
Subject(s) - family medicine , medicine , migraine , gerontology , psychiatry
Sometimes the observations by one astute clinician of one patient lead to new treatments. In 1966, Rabin et al in a study of propranolol to prevent angina, noted that a 59-year-old man reported that his migraines and angina improved on propranolol but the migraines returned after a crossover to placebo medication. Since then, propranolol has become a first-line agent for migraine prevention with increasing caveats, some real, others questionable.