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Memantine and NMDA Antagonism for Chronic Migraine: A Potentially Novel Therapeutic Approach?
Author(s) -
Spengos Konstantinos,
Theleritis Christos,
Paparrigopoulos Thomas
Publication year - 2008
Publication title -
headache: the journal of head and face pain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.14
H-Index - 119
eISSN - 1526-4610
pISSN - 0017-8748
DOI - 10.1111/j.1526-4610.2007.01016.x
Subject(s) - memantine , migraine , nmda receptor , medicine , concomitant , antagonist , antagonism , anesthesia , pharmacology , receptor
We present the case of a woman with chronic migraine who unexpectedly reported full remission of headache after memantine, an NMDA receptor antagonist, was administered for treating concomitant mild cognitive impairment. An underlying dose‐dependent effect of memantine on headache symptoms in chronic daily headache and chronic migraine could be assumed.