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Migraine and the Risk of Stroke, TIA, or Death in the UK (CME)
Author(s) -
Becker Claudia,
Brobert Gunnar P.,
Almqvist Per M.,
Johansson Saga,
Jick Susan S.,
Meier Christoph R.
Publication year - 2007
Publication title -
headache: the journal of head and face pain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.14
H-Index - 119
eISSN - 1526-4610
pISSN - 0017-8748
DOI - 10.1111/j.1526-4610.2007.00937.x
Subject(s) - migraine , medicine , stroke (engine) , odds ratio , confidence interval , observational study , relative risk , ischemic stroke , population , pediatrics , ischemia , mechanical engineering , environmental health , engineering
Background.— Previous observational studies have reported a higher risk of stroke in migraine patients. Objective.— We aimed to estimate the risk of stroke, transient ischemic attack (TIA), or death in migraineurs in the UK. Method.— We conducted a population‐based follow‐up study within the General Practice Research Database from 1994 to 2001. Results.— The relative risk (RR) of stroke in migraineurs compared with non‐migraineurs was 2.2 (95% confidence interval [CI] 1.7‐2.9). It was highest for patients with a migraine diagnosis recorded within 30 days prior to a stroke (odds ratio 11.1, 95% CI 5.69‐21.5). The RR of TIA in migraineurs compared with non‐migraineurs was 2.4 (95% CI 1.8‐3.3), the mortality of migraineurs was slightly decreased. Conclusion.— In our study, the RR of developing a stroke or a TIA was doubled in migraineurs as compared with non‐migraineurs, while that for death was close to unity.