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A Case of Hypertrophic Pachymeningitis With Prolonged Headache, Attributable to Epstein–Barr Virus
Author(s) -
Okuma Hirohisa,
Kobori Satoko,
Shinohara Yukito,
Takagi Shigeharu
Publication year - 2007
Publication title -
headache: the journal of head and face pain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.14
H-Index - 119
eISSN - 1526-4610
pISSN - 0017-8748
DOI - 10.1111/j.1526-4610.2007.00763_4.x
Subject(s) - medicine , headaches , magnetic resonance imaging , dura mater , antibody , virus , epstein–barr virus , pathology , surgery , radiology , immunology
Hypertrophic pachymeningitis is a condition characterized by significant chronic inflammatory thickening of the cranial dura mater, frequently presenting with symptoms such as headache and cranial neuropathy. In this report, we describe a very rare case of hypertrophic pachymeningitis, considered to be attributable to Epstein–Barr virus (EBV), which was diagnosed in a patient who visited our hospital with a complaint of ongoing severe headaches. The diagnosis was based on positive specific serum EBV antibody titers, with VCA‐IgM levels of less than 1:10, VCA‐IgG levels of 1:160, and EBNA levels of 1:40, as well as on the results of magnetic resonance imaging of the head with contrast media.