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Prophylaxis of Hemicrania Continua: Two New Cases Effectively Treated With Topiramate
Author(s) -
Brighina Filippo,
Palermo Antonio,
Cosentino Giuseppe,
Fierro Brigida
Publication year - 2007
Publication title -
headache: the journal of head and face pain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.14
H-Index - 119
eISSN - 1526-4610
pISSN - 0017-8748
DOI - 10.1111/j.1526-4610.2007.00733.x
Subject(s) - topiramate , medicine , anesthesia , side effect (computer science) , drug , migraine , pediatrics , pharmacology , epilepsy , psychiatry , computer science , programming language
Hemicrania continua (HC) is an uncommon and under‐recognized primary headache disorder characterized by a strictly unilateral continuous headache of moderate intensity with possible exacerbations and associated with ipsilateral autonomic features. HC has generally a prompt and enduring response to indomethacin although 25% to 50% of treated patients develop gastrointestinal side effects. These cases pose a difficult management challenge as no other drug is consistently effective in HC. Recently 2 HC patients responsive to topiramate treatment have been reported. Here we describe 2 more patients effectively treated with topiramate. Neither reported any side effects and one had persisting response for 6 months after drug withdrawal.