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Melatonin Responsive Hemicrania Continua
Author(s) -
Rozen Todd D.
Publication year - 2006
Publication title -
headache: the journal of head and face pain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.14
H-Index - 119
eISSN - 1526-4610
pISSN - 0017-8748
DOI - 10.1111/j.1526-4610.2006.00514_1.x
Subject(s) - melatonin , medicine , anesthesia
Hemicrania continua is one of the indomethacin‐responsive headache syndromes. There are very few effective alternative therapies for hemicrania continua, thus patients may require daily indomethacin for years. The risks of long‐term indomethacin include gastrointestinal and renal dysfunction. Melatonin is a pineal hormone with a chemical structure very similar to indomethacin. Recently, melatonin was shown to be effective for primary stabbing headache, another indomethacin‐responsive syndrome. Three cases of melatonin responsive hemicrania continua are now reported.