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Recurrence of Migraine With Aura Due to Tacrolimus Therapy in a Liver Transplant Recipient Successfully Treated With Sirolimus Substitution
Author(s) -
Toth Cory C.,
Burak Kelly,
Becker Werner
Publication year - 2005
Publication title -
headache: the journal of head and face pain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.14
H-Index - 119
eISSN - 1526-4610
pISSN - 0017-8748
DOI - 10.1111/j.1526-4610.2005.05053_1.x
Subject(s) - tacrolimus , sirolimus , discontinuation , medicine , headaches , migraine , aura , exacerbation , surgery , transplantation
We report the case of a female liver transplant recipient who developed a recurrence of severe migraine with aura while on tacrolimus therapy with subsequent remission of headache following discontinuation of tacrolimus and substitution with sirolimus therapy. Headaches in transplant‐recipient patients have become a new area of interest for headache specialists. In particular, immunosuppressant medications such as cyclosporine, tacrolimus, sirolimus, and OKT3 have been associated with development of headache syndromes in the transplant patient, exacerbation of previous headaches syndromes, and development of encephalopathies including headache as a clinical feature.