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Intracranial Hypertension Induced by Rofecoxib
Author(s) -
Jacob Saiju,
Rajabally Yusuf A.
Publication year - 2005
Publication title -
headache: the journal of head and face pain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.14
H-Index - 119
eISSN - 1526-4610
pISSN - 0017-8748
DOI - 10.1111/j.1526-4610.2005.05013.x
Subject(s) - rofecoxib , medicine , etiology , nonsteroidal , prostaglandin endoperoxide synthase , antiinflammatory drug , drug , anesthesia , cyclooxygenase , pharmacology , biochemistry , chemistry , enzyme
Several secondary causes are implicated in the etiology of idiopathic intracranial hypertension. Rofecoxib is a selective cyclo‐oxygenase (COX)‐2 inhibitor, now being increasingly used in place of nonselective nonsteroidal anti‐inflammatory drugs (NSAIDs). We report a case of intracranial hypertension in a 69‐year‐old man 3 weeks after the commencement of rofecoxib therapy with reversal of clinical findings on drug withdrawal.