Premium
Familial Hemiplegic Migraine, Neuropsychiatric Symptoms, and Erdheim‐Chester Disease
Author(s) -
Black David F.,
Kung Simon,
Sola Christopher L.,
Bostwick Michael J.,
Swanson Jerry W.
Publication year - 2004
Publication title -
headache: the journal of head and face pain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.14
H-Index - 119
eISSN - 1526-4610
pISSN - 0017-8748
DOI - 10.1111/j.1526-4610.2004.04174.x
Subject(s) - medicine , erdheim–chester disease , migraine , familial hemiplegic migraine , disease , physical medicine and rehabilitation , dermatology , psychiatry , pathology , histiocytosis , migraine with aura , aura
We report the occurrence of unilateral cerebral hemisphere edema with subsequent cortical laminar necrosis in the setting of familial hemiplegic migraine (FHM) and permanent neurologic sequelae after resolution of an attack in 1 patient. Contemporaneous with this severe attack of FHM, the patient was found to exhibit multiple systemic and neurological symptoms referable to Erdheim‐Chester disease (a rare non‐Langerhans cell histiocytosis) that was confirmed by bone biopsy. This case demonstrates the severity possible with a migrainous infarction associated with FHM. The co‐occurrence of two such rare entities in 1 patient suggests a possible relationship.