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The Effect of Hyperventilation in Cluster Headache Patients
Author(s) -
Antonaci Fabio,
Zhao JingMing,
Schaanning Jan,
Sand Trond,
Sjaastad Ottar
Publication year - 1991
Publication title -
headache: the journal of head and face pain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.14
H-Index - 119
eISSN - 1526-4610
pISSN - 0017-8748
DOI - 10.1111/j.1526-4610.1991.hed3103146.x
Subject(s) - hyperventilation , cluster headache , anesthesia , cluster (spacecraft) , medicine , migraine , computer science , programming language
SYNOPSIS The effect of voluntary hyperventilation was assessed in 22 cluster headache patients (8 in a cluster period and14 in a remission) and 19 healthy individuals. Using an ear oximeter and a capnograph with a nasal probe, the oxygen saturation (SaO 2 ) and the end‐tidal CO 2 were monitored continuously. During the hyperventilation per se, cluster headache patients and controls showed absolute values of end‐tidal CO 2 and of SaO 2 Of the Same order of magnitude. In the posthyperventilation phase, however, the average of the lowest SaO 2 levels was lower in controls than in cluster headache patients. In the posthyperventilation phase, headache patients outside the cluster period showed a trend more similar to that of the controls with respect to SaO 2 than did those inside the cluster period. The observed discrepancy might, if reproducible, be a consequence of an altered chemoreceptor sensitivity in cluster headache patients during the bout.

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