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Adverse Reactions to Iopamidol and Iohexol Myelography with Special Attention to Headache: Role of Myelographic Technique
Author(s) -
Sobel David F.,
Rowe Rekarda,
Zyroff Jack,
Koziol James A.,
Frost Francine,
Krupsaw Jean
Publication year - 1989
Publication title -
headache: the journal of head and face pain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.14
H-Index - 119
eISSN - 1526-4610
pISSN - 0017-8748
DOI - 10.1111/j.1526-4610.1989.hed2908519.x
Subject(s) - iopamidol , iohexol , medicine , nausea , myelography , vomiting , incidence (geometry) , anesthesia , adverse effect , contrast medium , radiology , psychiatry , physics , optics , renal function , spinal cord
SYNOPSIS In order to identify those myelographic risk factors associated with a higher incidence of adverse effects, myelographic technique, patient variables and post‐myelographic symptoms were prospectively recorded in a group of 152 patients studied with iopamidol and in a second group of 28 patients studied with iohexol. None of the technical factors studied were identified to have a statistically significant relationship with the incidence of adverse reactions. Older patients fared better than younger patients in both groups. Overall, there was a lower incidence of side effects in the iopomidol group (29%) than in the iohexol group (50%). Headache, nausea, and vomiting were the most frequent reactions seen.