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Prophylactic Treatment of Cluster Headache with Budipine
Author(s) -
Krüger H.,
Kohlhepp W.,
Reimann G.,
Przuntek H.
Publication year - 1988
Publication title -
headache: the journal of head and face pain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.14
H-Index - 119
eISSN - 1526-4610
pISSN - 0017-8748
DOI - 10.1111/j.1526-4610.1988.hed2805344.x
Subject(s) - cluster headache , prophylactic treatment , medicine , migraine , cluster (spacecraft) , anesthesia , pediatrics , computer science , programming language
SYNOPSIS For two years we have tested the prophylactic efficacy of budipine for the treatment of cluster headache. The open study was carried out on 27 men and 8 women. 23 patients suffered from episodic and 2 from chronic cluster headache. 7 patients had cluster‐migraine, and 3 chronic paroxysmal hemicrania. 20 patients were free of cluster headache attacks 2–6 days after beginning daily prophylactic budipine therapy with 15–60 mg. 14 patients showed a markedly decreased frequency of attacks and the intensity of persisting attacks was diminished. One patient reported only a slight improvement. There were no non‐responders to budipine therapy. 10 patients showed only mild budipine side effects. Budipine was found very effective for treatment of cluster headache.