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A Case of Hemiplegic Migraine Treated with Flunarizine
Author(s) -
Tobita Muneshige,
Hino Masatoshi,
Ichikawa Nobumichi,
Takase Sadao,
Ogawa Akira
Publication year - 1987
Publication title -
headache: the journal of head and face pain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.14
H-Index - 119
eISSN - 1526-4610
pISSN - 0017-8748
DOI - 10.1111/j.1526-4610.1987.hed2709487.x
Subject(s) - flunarizine , migraine , hemiparesis , medicine , anesthesia , cerebral blood flow , vasodilation , cardiology , angiography , calcium
SYNOPSIS A patient with hemiplegic migraine who was treated successfully with flunarizine is presented. A fifteen‐year‐old boy developed right hemiparesis during several migraine attacks. Regional cerebral blood flow (CBF) measurement using intravenously injected xenon 133 showed that the CBF was about 10‐15% lower in left fronto‐temporo‐parietal regions than that on the contra‐lateral side. After the treatment with flunarizine at a dose of 10 mg/day, he has been free of migraine attacks and hemiparesis disappeared. Regional CBF 1 month after treatment showed no decrease in any region of the brain. The findings indicate that flunarizine reversed the neurological deficits by increasing CBF by its vasodilating action.