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Nimodipine versus Flunarizine in Common Migraine: A Controlled Pilot Trial
Author(s) -
Bussone G.,
Baldini S.,
D'Andrea G.,
Cananzi A.,
Frediani F.,
Caresia L.,
Milone F. Ferro,
Boiardi A.
Publication year - 1987
Publication title -
headache: the journal of head and face pain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.14
H-Index - 119
eISSN - 1526-4610
pISSN - 0017-8748
DOI - 10.1111/j.1526-4610.1987.hed2702076.x
Subject(s) - flunarizine , nimodipine , medicine , migraine , anesthesia , antagonist , randomized controlled trial , adverse effect , pharmacology , calcium , receptor
SYNOPSIS The effects of Nimodipine and Flunarizine, both calcium‐antagonist drugs, in the prevention of common migraine were investigated in a double‐blind randomized parallel study. Five patients of the 30 included in the study dropped out because of adverse reactions. Two were treated with Nimodipine and three with Flunarizine. Our results suggest a similar efficacy for both drugs, although Nimodipine seems to have a shorter latency of effect. Nimodipine is a useful new agent for common migraine prevention.