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Lithium‐Triggered Chronic Cluster Headache
Author(s) -
Brainin M.,
Eisenstädter A.
Publication year - 1985
Publication title -
headache: the journal of head and face pain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.14
H-Index - 119
eISSN - 1526-4610
pISSN - 0017-8748
DOI - 10.1111/j.1526-4610.1985.hed2507394.x
Subject(s) - cluster headache , lithium carbonate , discontinuation , lithium (medication) , headaches , lithium therapy , medicine , cluster (spacecraft) , pediatrics , bipolar disorder , psychiatry , migraine , chemistry , ion , organic chemistry , computer science , ionic bonding , programming language
SYNOPSIS Lithium carbonate, usually helpful in the treatment of cluster headache, showed a paradoxical effect in a patient now being seen for over one year. Chronic cluster headache developed after she had been taking lithium for more than eight years for psychiatric indications. Only by total discontinuation of lithium therapy could a complete remission of the headaches be brought about. This effect was observed repeatedly. It is suggested that a chronic effect of lithium at the receptor sites of the central trigeminovascular pathways plays a role.