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Ketotifen in the Treatment of Chronic Cluster Headache
Author(s) -
Split Wojciech,
Szmidt Miroslaw,
Prusinski Antoni,
Rozniecki Jerzy
Publication year - 1984
Publication title -
headache: the journal of head and face pain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.14
H-Index - 119
eISSN - 1526-4610
pISSN - 0017-8748
DOI - 10.1111/j.1526-4610.1984.hed2403147.x
Subject(s) - ketotifen , cluster headache , medicine , histamine , asthma , drug , mast cell , drug treatment , cluster (spacecraft) , anesthesia , gastroenterology , pharmacology , immunology , migraine , computer science , programming language
SYNOPSIS Based on observations indicating histamine release in cluster headache, Ketotifen was given to 15 patients suffering from a chronic form of this disease. The drug shows a mast cell membrane stabilizing action which proved effective in the treatment of bronchial asthma. It was administered in dosage of 1 mg 3 times daily for 8 weeks. Full remission was achieved in 8 patients. A considerable improvement was noted in 2 cases, a moderate improvement in 3, and only a slight improvement in 2 cases.