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Fetal Demise in a Migraine Patient on Propranolol
Author(s) -
Featherstone Harvey J.
Publication year - 1983
Publication title -
headache: the journal of head and face pain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.14
H-Index - 119
eISSN - 1526-4610
pISSN - 0017-8748
DOI - 10.1111/j.1526-4610.1983.hed2305213.x
Subject(s) - propranolol , migraine , headaches , medicine , anesthesia , demise , pregnancy , ischemia , fetus , vasomotor , cardiology , surgery , biology , law , genetics , political science
SYNOPSIS The safety of propranolol therapy early in pregnancy is not known. A case is reported in which fatal demise occurred at 12 weeks and was related to propranolol use for migraine headaches. Propranolol has been associated with reduced umbilical blood flow in animals; this effect may be augmented and cause severe fatal ischemia in patients with the vasomotor instability of migraine.