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The Five Hour Glucose Tolerance Test and Effect of Low Sucrose Diet in Migraine
Author(s) -
Dexter James D.,
Roberts John,
Byer John A.
Publication year - 1978
Publication title -
headache: the journal of head and face pain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.14
H-Index - 119
eISSN - 1526-4610
pISSN - 0017-8748
DOI - 10.1111/j.1526-4610.1978.hed1802091.x
Subject(s) - medicine , morning , hypoglycemia , migraine , meal , regimen , glucose tolerance test , diabetes mellitus , sucrose , impaired glucose tolerance , gastroenterology , anesthesia , endocrinology , type 2 diabetes , chemistry , biochemistry , insulin resistance
SYNOPSIS Seventy‐four patients were evaluated who suffered from migraine and associated their attacks to the mid‐morning or mid‐afternoon fasting state. These seventy‐four patients underwent a standard five hour, 100 gram glucose tolerance test. The glucose tolerance curves of six of the patients were classified diabetic and fifty‐six patients exhibited a curve consistent with degrees of reactive hypoglycemia, i.e., serum glucose of less than 65 mg% or a drop of 75 mg% within one hour. Following dietary therapy with a low sucrose, six meal regimen, all patients who demonstrated a diabetic glucose tolerance curve showed an improvement of greater than 75%, and three have been headache free. Of the fifty‐six patients who showed reactive hypoglycemia curves, forty‐three returned for follow‐up after dietary instruction. Of those forty‐three patients 27, (63%) showed greater than 75% improvement, 17 (40%) showed 50 to 75% improvement and 4 (9%) showed 25 to 50% improvement.