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Osteal Complications as First Manifestation in a Patient with Primary Sjögren's Syndrome and with Associated Distal Tubular Acidosis (Type 1) and Chronic Renal Insufficiency
Author(s) -
Díaz Rodríguez C,
González Rivero C,
Trinidad San José JC,
Del Río Romero D,
Moreno Fernández A,
Granja Romero E
Publication year - 2004
Publication title -
therapeutic apheresis and dialysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.415
H-Index - 53
eISSN - 1744-9987
pISSN - 1744-9979
DOI - 10.1111/j.1526-0968.2003.00122.x
Subject(s) - medicine , renal tubular acidosis , distal renal tubular acidosis , complication , acidosis , osteomalacia , interstitial nephritis , gastroenterology , kidney , osteoporosis
Renal affection is among the complications associated with the Sjögren's Syndrome. Tubulo‐interstitial nephritis constitutes the most frequent renal lesion and distal tubular acidosis (Type 1) is the most important clinical manifestation of this tubular dysfunction, although the occurrence of chronic renal insufficiency is not an uncommon finding in the presence of distal renal tubular acidosis. Osteomalacia is a clinical consequence of tubular acidosis caused by buffering of H + in the bone. We present the case of a woman with osteal complication a year before being diagnosed with primary Sjögren's Syndrome and with distal tubular acidosis and renal insufficiency associated at diagnosis.