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The Effect of Fluid Viscosity on the Hemodynamic Energy Changes During Operation of the Pulsatile Ventricular Assist Device
Author(s) -
Ahn Chi Bum,
Son Kuk Hui,
Lee Jung Joo,
Choi Jaesoon,
Song Seung Joon,
Jung Jae Seung,
Lee Sung Ho,
Son Ho Sung,
Sun Kyung
Publication year - 2011
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.2011.01350.x
Subject(s) - pulsatile flow , hemodynamics , blood viscosity , viscosity , hematocrit , vascular resistance , cannula , blood flow , cardiology , materials science , chemistry , biomedical engineering , medicine , surgery , composite material
Blood viscosity during operation of ventricular assist device (VAD) can be changed by various conditions such as anemia. It is known generally that the blood viscosity can affect vascular resistance and lead to change of blood flow. In this study, the effect of fluid viscosity variation on hemodynamic energy was evaluated with a pulsatile blood pump in a mock system. Six solutions were used for experiments, which were composed of water and glycerin and had different viscosities of 2, 2.5, 3, 3.5, 4, and 4.5 cP. The hemodynamic energy at the outlet cannula was measured. Experimental results showed that mean pressure was increased in accordance with the viscosity increase. When the viscosity increased, the mean pressure was also increased. However, the flow was decreased according to the viscosity increase. Energy equivalent pressure value was increased according to the viscosity‐induced pressure rise; however, surplus hemodynamic energy value did not show any apparent changing trend. The hemodynamic energy made by the pulsatile VAD was affected by the viscosity of the circulating fluid.