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A Three‐Dimensional Bioprinting System for Use With a Hydrogel‐Based Biomaterial and Printing Parameter Characterization
Author(s) -
Song SeungJoon,
Choi Jaesoon,
Park YongDoo,
Lee JungJoo,
Hong So Young,
Sun Kyung
Publication year - 2010
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.2010.01143.x
Subject(s) - biofabrication , tissue engineering , nozzle , 3d bioprinting , regenerative medicine , 3d printing , biomedical engineering , computer science , biomaterial , nanotechnology , engineering drawing , materials science , mechanical engineering , engineering , chemistry , biochemistry , cell
Bioprinting is an emerging technology for constructing tissue or bioartificial organs with complex three‐dimensional (3D) structures. It provides high‐precision spatial shape forming ability on a larger scale than conventional tissue engineering methods, and simultaneous multiple components composition ability. Bioprinting utilizes a computer‐controlled 3D printer mechanism for 3D biological structure construction. To implement minimal pattern width in a hydrogel‐based bioprinting system, a study on printing characteristics was performed by varying printer control parameters. The experimental results showed that printing pattern width depends on associated printer control parameters such as printing flow rate, nozzle diameter, and nozzle velocity. The system under development showed acceptable feasibility of potential use for accurate printing pattern implementation in tissue engineering applications and is another example of novel techniques for regenerative medicine based on computer‐aided biofabrication system.