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Cleveland Clinic PediPump Lamb Cadaver Fitting Studies
Author(s) -
Cingoz Faruk,
Fukamachi Kiyotaka,
Ootaki Yoshio,
Kamohara Keiji,
Akiyama Masatoshi,
Ootaki Chiyo,
Kopcak Michael W.,
Liu Jenny,
Noecker Angela,
Dudzinski Dave,
Smith William A.,
Duncan Brian W.
Publication year - 2007
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.2007.00400.x
Subject(s) - medicine , thoracotomy , inflow , ventricular assist device , cannula , cadaver , outflow , thoracic cavity , median sternotomy , surgery , cardiology , biomedical engineering , heart failure , geology , oceanography
We are developing the PediPump, a magnetically suspended, mixed‐flow pump, as an implantable pediatric ventricular assist device (VAD). Lamb cadaver fitting studies were performed to determine the optimal pump location and optimal design of the inflow and outflow conduits for chronic in vivo studies. A prototype of the PediPump right and left ventricular assist devices (RVAD and LVAD, respectively) were implanted via a sternotomy or left thoracotomy in four lamb cadavers (3.7–34.2 kg). Via a sternotomy, the RVAD and LVAD required long inflow cannulas when placed into the right or left thoracic cavities, respectively. Via a left thoracotomy, with both pumps implanted in the left thoracic cavity, the RVAD required a 70° inflow cannula and a bent outflow graft while the LVAD required a 130° inflow cannula and a straight outflow graft. In conclusion, left thoracotomy provided optimal fitting for both LVAD and RVAD for the small lamb model.