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Influence of Flow Design on Microcirculation in Conditions of Undulation Pump‐Left Ventricle Assist Device Testing
Author(s) -
Dobšák Petr,
Novakova Marie,
Baba Atsushi,
Vasku Jaromir,
Isoyama Takashi,
Saito Itsuro,
Abe Yusuke,
Chinzei Tsuneo,
Imachi Kou
Publication year - 2006
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.2006.00244.x
Subject(s) - pulsatile flow , microcirculation , ventricle , peristaltic pump , microvessel , continuous flow , medicine , cardiology , biomedical engineering , mechanics , physics , angiogenesis , meteorology
To study the microvessels in bulbar conjunctiva, we conducted an experiment in goat with a pneumatically driven left heart bypass pump, which was replaced with an undulation pump‐left ventricle assist device for 9 days. Three flow patterns were tested: complete pulsatile, continuous, and percentage of pulsatile. We studied the morphology of arterioles and venules of the bulbar conjunctiva using photograph records. The setting up of continuous flow caused global vasoconstriction (significant in venules— P < 0.05). During the pumping in the pulsatile and percentage of pulsatile modes, no significant changes of microvessel morphology were observed. The findings described could point to some disturbances in the microcirculatory bed in conditions of continuous flow.