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A Complete Mock Circulation Loop for the Evaluation of Left, Right, and Biventricular Assist Devices
Author(s) -
Timms Daniel,
Hayne Mark,
McNeil Keith,
Galbraith Andrew
Publication year - 2005
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.2005.29094.x
Subject(s) - pulsatile flow , circulatory system , systemic circulation , hemodynamics , cardiology , loop (graph theory) , perfusion , feedback loop , natural circulation , blood circulation , closed loop , computer science , medicine , biomedical engineering , engineering , physics , mechanics , mathematics , control engineering , computer security , combinatorics , traditional medicine
A new mock circulation loop was developed to replicate the necessary features of the systemic and pulmonic circulatory systems, including pulsatile left and right ventricles coupled with vascular compliances and resistances. A brief description of the mock loop construction is provided before results are presented confirming the recreation of perfusion rates and pressures found in the natural systemic and pulmonic vascular trees for a normal and failing heart at rest. This rig provides the ability to evaluate the hemodynamic effect of left, right, and biventricular assist devices in vitro. The small and compact mock circulation rig has the potential to reduce device evaluation costs by simulating the natural circulatory system, thus providing valuable device performance feedback prior to expensive in vivo animal trials.