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Valve Replacement Surgery in Patients With End‐stage Renal Disease: Long‐term Results
Author(s) -
Gultekin Bahadir,
Ozkan Suleyman,
Uguz Emrah,
Atalay Hakan,
Akay Tankut,
Arslan Ahmet,
Sezgin Atilla,
Ozdemir Nurhan,
Tasdelen Atilay,
Aslamaci Sait
Publication year - 2005
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.2005.00171.x
Subject(s) - medicine , dialysis , surgery , hemodialysis , renal replacement therapy , valve replacement , life expectancy , transplantation , end stage renal disease , aortic valve replacement , warfarin , mitral valve replacement , kidney disease , valvular heart disease , mitral valve , atrial fibrillation , stenosis , population , environmental health
Background:  The life expectancy of patients with chronic renal failure who are dependent on dialysis is very poor. This study was undertaken to determine time‐related outcomes in dialysis patients requiring cardiac valve replacement. Methods:  From 1994 to 2001, 29 end‐stage renal disease (ESRD) patients on hemodialysis (HD) program underwent 30 valve replacement operations: 29 received mechanical valves (97%), and one received bioprosthetic valves. The sites of valve replacement were 11 aortic (36.7%), 18 mitral (60%), and one both aortic and mitral (3.3%). Mean age was 42.46 ± 14.26 years (range 17–75 years). Follow‐up was completed in 28 patients (96.5%). Results:  Early postoperative mortality (in the first 30 days) was 3.4% ( n  = 1). The overall estimated Kaplan–Meier survival was 56.7% at 36 months, 46.7% at 60 months, and 43.3% at 96 months. HD program was discontinued for two patients after renal transplantation in the follow‐up period. All patients, except the one with bioprosthesis, used warfarin sodium for anticoagulation and none of them had bleeding. One of the patients had a major cerebrovascular accident (CVA) and another one had a minor CVA at the follow‐up (6.7%). Conclusions:  Life quality is better and life expectancy is longer after valve replacement in ESRD patients who have valvular disease. Also, longer life expectancy increases the probability for finding donors for kidney transplantation.

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