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Is the Guideline the Cause of Structural Failure in Current Polyester Vascular Prostheses? An Experimental Study
Author(s) -
Kawata Mitsuhiro,
Takamoto Shinichi,
Morota Tetsuro,
Ono Minoru,
Motomura Noboru,
Murakami Arata,
Suematsu Yoshihiro
Publication year - 2005
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.2005.00135.x
Subject(s) - guideline , polyester , current (fluid) , medicine , materials science , biomedical engineering , composite material , pathology , engineering , electrical engineering
To evaluate the impact of the guideline on the structural failure of current polyester vascular prostheses, we studied seven unsealed polyester vascular prostheses. An accelerated time test was used for assessing degradation of polymeric medical materials at pH 7.4 in phosphate buffer at a temperature of 95°C. Probe burst strength was determined on the guideline and on standard parts of the prostheses during the accelerated time test. Weight‐average molecular weights of the guideline and of the standard parts in all knitted grafts during the accelerated time test were measured. The guideline was significantly weaker than the standard parts in most prostheses. The guideline had significantly lower values of weight‐average molecular weights than the standard parts in most knitted grafts. This study showed that guideline degeneration was one factor responsible for the structural failure of some current polyester vascular prostheses.