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The Most Profitable Use of Flow Visualization in the Elimination of Thrombus from a Monopivot Magnetic Suspension Blood Pump
Author(s) -
Yamane Takashi,
Maruyama Osamu,
Nishida Masahiro,
Toyoda Masahiro,
Tsutsui Tatsuo,
Jikuya Tomoaki,
Shigeta Osamu,
Sankai Yoshiyuki
Publication year - 2004
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.2004.47110.x
Subject(s) - visualization , thrombus , washout , flow visualization , suspension (topology) , peristaltic pump , flow (mathematics) , biomedical engineering , materials science , centrifugal pump , mechanics , computer science , mechanical engineering , impeller , engineering , physics , mathematics , cardiology , medicine , homotopy , pure mathematics
The purpose of this study was to eliminate fluid dynamic causes of thrombus formation for the monopivot magnetic suspension centrifugal pump under development with the aid of flow visualization as an indirect measurement tool for animal experiments. The formation of thrombus observed in early animal experiments was successfully overcome by combining the multiple washout holes at the center into a single hole, optimizing the hole diameter, and eliminating the pivot gap. Flow visualization was used to optimize the washout hole diameter influencing the flow around the pivot. In animal experiments flow visualization showed that the contours of thrombus corresponded to shear rates of 300 s −1 or 1300–1700 s −1 . It was found that flow visualization is a useful technique to predict locations where low shear thrombi form and to optimize the pump design in the development stage.