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Development of a Novel Polyimide Hollow‐fiber Oxygenator
Author(s) -
Niwa Motohiro,
Kawakami Hiroyoshi,
Nagaoka Shoji,
Kanamori Toshiyuki,
Morisaku Kazuko,
Shinbo Toshio,
Matsuda Toshiaki,
Sakai Kazunari,
Kubota Sunao
Publication year - 2004
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.2004.07257.x
Subject(s) - polyimide , materials science , oxygenator , fiber , hollow fiber membrane , composite material , membrane oxygenator , membrane , chemistry , layer (electronics) , surgery , medicine , cardiopulmonary bypass , biochemistry , extracorporeal membrane oxygenation
We have developed a membrane oxygenator using a novel asymmetric polyimide hollow fiber. The hollow fibers are prepared using a dry/wet phase‐inversion process. The gas transfer rates of O 2 and CO 2 through the hollow fibers are investigated in gas–gas and gas–liquid systems. The polyimide hollow fiber has an asymmetric structure characterized by the presence of macrovoids, and the outer diameter of the hollow fiber is 330 µm. It is found that the polyimide hollow‐fiber oxygenator can enhance the gas transfer rates of O 2 and CO 2 , and that the hollow fiber provides excellent blood compatibility in vitro and in vivo.