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New Aspects on the Role of Blood Pressure and Arterial Stiffness in Mechanical Assistance by Intra‐aortic Balloon Pump: In‐vitro Data and Their Application in Clinical Practice
Author(s) -
Papaioannou Theodoros G.,
Mathioulakis Dimitrios S.,
Stamatelopoulos Kimon S.,
Gialafos Elias J.,
Lekakis John P.,
Nanas John,
Stamatelopoulos Stamatios F.,
Tsangaris Sokratis G.
Publication year - 2004
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.2004.00080.x
Subject(s) - hemodynamics , cardiogenic shock , medicine , intra aortic balloon pump , cardiology , blood pressure , intra aortic balloon pumping , myocardial infarction , arterial stiffness , shock (circulatory) , aortic pressure , circulatory system , balloon
Despite the well‐known beneficial effects of the intra‐aortic balloon pump (IABP) generally, there are still some clinical conditions accompanied by IABP ineffectiveness. The aim of this study was the investigation of the independent effects of arterial stiffness and blood pressure on acute IABP effectiveness. For this purpose, a mock circulatory system and 20 patients with cardiogenic shock due to acute myocardial infarction, were employed. It was shown that IABP acute efficiency was determined primarily by arterial compliance (AC) rather than blood pressure alone. IABP induced low hemodynamic effects in patients with systolic blood pressure > 80 mm Hg but with increased AC, whereas IABP resulted in greater hemodynamic effectiveness in cases with systolic pressure < 70 mm Hg but lower AC. The present study provides evidence concerning the hemodynamic conditions, which might lead to optimization of IABP or to the prediction of its acute hemodynamic performance, based on both measurements of AC and blood pressure.