Premium
Effect of Adaptive Pulse Train Duration on Latissimus Dorsi Blood Flow
Author(s) -
Gealow Kendra,
Solien Eric,
Bianco Richard,
Grandjean Pierre
Publication year - 1997
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.1997.tb04659.x
Subject(s) - cardiomyoplasty , blood flow , latissimus dorsi muscle , pulse (music) , contraction (grammar) , stimulation , pulse duration , blood pressure , medicine , pulse pressure , pulse wave , muscle contraction , anesthesia , pulse rate , cardiology , biomedical engineering , materials science , anatomy , voltage , physics , heart failure , laser , power (physics) , quantum mechanics , optics
Blood flow, intramuscular pressure, and stroke work of the trainedlatissimus dorsi muscle (LD) were measured during electrical stimulation atcontraction ratesbetween 20 and 160/min using pulse trains of 2 to 6 pulses in length. Epimysialelectrodes and intramuscular pressure sensors were implanted in the LD of 5dogs. The muscleremained in situ. After 12 weeks of a progressive training protocol, LD bloodflow (BF) was measured using an ultrasonic flow probe and work (SW) wasdetermined from the measuredforce and shortening. For pulse trains of 2 or 3 pulses, BF increased with rate,and SW was maintained at all rates. For 4 pulses, BF and SW decreased when thecontraction rateexceeded 120/min. SW decreased above 100/min and 80/min for 5 and 6 pulses,respectively. An upper rate limit dependent upon the pulse train durationexists above which BF and SWdecline. Exceeding these upper rate limits should be avoided incardiomyoplasty. Excessive stimulation rates could be detrimental to the muscleby creating a metabolicinsufficiency or ischemia. The cardiac assistance benefit is compromised as SWdeclines during high contraction rates of long pulse train duration.