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Development of an Intravascular Pumping Oxygenator Using a New Silicone Membrane
Author(s) -
Sueda Taijiro,
Fukunaga Shintaro,
Morita Satoru,
Sueshiro Masafumi,
Hirai Shinji,
Okada Kenji,
Orihashi Kazumasa,
Matsuura Yuichiro
Publication year - 1997
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.1997.tb00703.x
Subject(s) - oxygenator , membrane oxygenator , circulatory system , hollow fiber membrane , biomedical engineering , blood flow , oxygenation , materials science , extracorporeal membrane oxygenation , chemistry , anesthesia , chromatography , fiber , medicine , cardiopulmonary bypass , cardiology , composite material
A new intravascular pumping oxygenator (IVPO) was developed for intravascular gas exchange and circulatory assistance in critically ill patients with respiratory and circulatory failure. The IVPO utilizes new silicone hollow fibers (diameter. 1 mm: membrane width, 50 μm) and consists of two driving tubes for the oxygenation and pumping of circulating blood. The performance characteristics of the IVPO were studied using an experimental ex vivo model. With a mean hemoglobin concentration of 10.5 ± 2.3 g/dl, total oxygen transfer was 5.6 ± 1.5 ml/min at a blood flow of 200 ml/min and 6.3 ± 2.2 ml/min at a blood flow of 250 ml/min. Total CO 2 transfer was 3.8 ± 1.4 ml/min at a blood flow of 200 ml/min and 4.2 ± 1.6 ml/min at a blood flow of 250 ml/min during IVPO pumping. This preliminary experiment demonstrated that the IVPO has the capacity to function both as a circulatory assist pump and as an intravascular hollow fiber oxygenator.