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Helium/Oxygen Breathing Improves Hypoxemia after Cardiac Surgery
Author(s) -
Yahagi Naoki,
Kumon Keiji,
Haruna Masaki,
Watanabe Yasuhiko,
Matsui Junk,
Hayashi Hideaki,
Tanigami Hironobu,
Takamoto Shinichi
Publication year - 1997
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/j.1525-1594.1997.tb00694.x
Subject(s) - medicine , hypoxemia , anesthesia , oxygenation , pulmonary shunt , oxygen , pulmonary compliance , inhalation , ventilation (architecture) , cardiology , respiratory system , hemodynamics , chemistry , mechanical engineering , organic chemistry , engineering
The effects of helium/oxygen (He/O 2 ) on oxygen‐ation (respiratory index [Pao 2 ,/Fio 2 ] and inuapulmonary shunt [Qs/Qt]) and on lung parameters (dynamic compliance [Cdyn] and peak inspiratory pressure [PIP]) were studied in 12 patients. After cardiac surgery, they had impairment of oxygen‐ation without physiological findings and with normal chest radiographs despite having a positive end expiratory pressure of up to 10 cm H 2 O. After 90 min of inhalation of He/O 2 ., oxy‐genation had improved significantly; that is, Pao 2 /Fio 2 , in creased significantly (from 113 to 174 mm Hg; mean values are given; p < 0.01), and there was a significant fall in Qs/Qt (from 29 to 19%; p < 0.01) together with an increase in Cdyn (from 60 ml/cm H 2 O to 64 mVcm H 2 O; p < 0.05). These results suggest that HeiO 2 may have improved oxygenation by recruiting previously obstructed small airways and alveoli.